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对24例经肠镜检查初步诊断为直肠、结肠癌的患者进行18FDG-PET显像研究,评价18FDG-PET对大肠癌诊断、分期及治疗计划的价值。结果表明,24例病理证实为大肠癌的患者,23例局部18FDG摄取增高(SUVmax=7.09±3.26,2.98~12.2)1。8FDG-PET对于肿瘤原发病灶诊断准确率为95%(23/24),假阴性1例,8例远处转移全部检出;对于单纯局部(主要为第1站)淋巴结转移灵敏度为50%(8/16),特异性为100%;改变了33%(8/24)患者的治疗方案。因此,18FDG-PET对大肠癌原发病灶诊断灵敏度高,假阴性率低,但鉴别原发病灶早期局部侵犯程度作用有限;18FDG-PET对于淋巴结、肝、骨骼等远处转移探测效率高;18FDG-PET对大肠癌的分期和治疗计划制定有一定的价值。
To evaluate the value of 18FDG-PET in the diagnosis, staging and treatment of colorectal cancer in 24 patients with primary diagnosis of rectal cancer and colon cancer by enteroscopy. The results showed that 24 patients with pathologically confirmed colorectal cancer, 23 cases of local 18FDG uptake increased (SUVmax = 7.09 ± 3.26,2.98 ~ 12.2) 1.8FDG-PET for the diagnosis of primary tumor of the tumor was 95% accuracy (23/24 ), False negative in 1 case, and distant metastasis in 8 cases were all detected. The sensitivity was only 50% (8/16) and specificity was 100% for simple local (mainly the first station) lymph node metastasis. The sensitivity was 33% (8) / 24) Patient’s treatment regimen. Therefore, 18FDG-PET has high diagnostic sensitivity to primary lesions of colorectal cancer with low false-negative rate, but it has limited effect of identifying the early local invasion of primary lesions. 18FDG-PET has high detection efficiency for distant metastasis such as lymph nodes, liver and bone, 18FDG -PET has certain value for the staging and treatment planning of colorectal cancer.