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目的 :探讨153 Sm -EDTMP对肺癌骨转移的治疗价值。方法 :10 5例肺癌骨转移有不同程度骨痛 ,对照组30例 ,化疗组 5 3例 ,化疗 +153 Sm组 2 2例 ,采用化疗加153 Sm -EDTMP治疗。结果 :对照组、化疗组及化疗 +153 Sm组癌疼痛缓解有效率分别为 2 6 .7% ,41.5 %及 86 .4% (P <0 .0 5 ) ,而患者生存期分别为 2 .5、4.5月及7.5月 (P <0 .0 5 )。结论 :153 Sm -EDTMP对轻中度及重度癌疼痛治疗均有效 ,能提高患者生活质量及延长生存期限
Objective: To investigate the value of 153 Sm-EDTMP in treatment of bone metastasis of lung cancer. Methods: 105 cases of bone metastasis of lung cancer with varying degrees of bone pain, control group 30 cases, chemotherapy group 53 cases, chemotherapy +153 Sm group 22 cases were treated with chemotherapy plus 153 Sm-EDTMP. Results: The effective rates of cancer pain relief in control group, chemotherapy group and chemotherapy +153 Sm group were respectively 26.7%, 41.5% and 86.4% (P <0.05), but the survival time was 2. May, April and July, May (P <0.05). Conclusion: 153 Sm-EDTMP is effective in the treatment of mild to moderate and severe cancer pain, which can improve the quality of life and extend the life span of patients