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目的:应用纹理特征分析技术评估颞下颌关节紊乱病（temporomandibular disorders，TMD）患者盘后附着组织的组织学改变。方法:对2018年4月至2020年4月于解放军总医院海南医院颞下颌关节病门诊就诊的33例TMD患者［女性18例，男性15例，年龄（28.3±11.6）岁］行颞下颌关节MRI检查。按关节盘移位情况分为正常位置（normal position，NP）组（29侧）、可复性关节盘移位（disk displacement with reduction，DDwR）组（14侧）及不可复性关节盘移位（disk displacement without reduction，DDwoR）组（23侧）。采用灰度共生矩阵法在开口位斜矢状位质子密度加权成像上分析盘后附着组织纹理特征，其纹理特征参数主要包括角二阶矩、对比度、自相关、逆差矩及熵。采用Kruskal-Wallis n H检验、单因素方差分析及受试者工作特征曲线（receiver operating characteristic curve，ROC）分析盘后附着组织的各项纹理特征参数差异。n 结果:盘后附着组织的角二阶矩、对比度、自相关及逆差距各组间差异无统计学意义（n P>0.05）。NP组及DDwR组的熵（分别为3.98±0.44和4.20±0.52）均显著大于DDwoR组（3.70±0.38）（n P0.05). The entropy in NP group (3.98±0.44) and DDwR group (4.20±0.52) presented significant higher than that in DDwoR group (3.70±0.38) (n P<0.05). ROC analysis for the entropy demonstrated that the area under the curve was 0.70 when differentiating NP and DDwR (cut-off value 0.38, sensitivity 82.61%, specificity 55.17%), and was 0.79 when differentiating DDwR and DDwoR (cut-off value 0.47, sensitivity 82.61%, specificity 64.29%).n Conclusions:Texture entropy could be primarily used to evaluate the histological and pathological changes of the retrodiscal tissue in the TMD patients.