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1985年4月在美国召开了爱滋病(AIDS)治疗药物的国际会议。会议认为引起AIDS的有三类病毒,即Montagnier发现的与淋巴腺有关的LAV、Gallo分离的与T淋巴细胞有关的HTLV-Ⅲ和Levy发现的退行性病毒ARV。目前已发现了6种抑制细胞复制的抗AIDS药物。苏拉明钠(Suramin Sodium)是萘三磺酸(naphthalene trisulfonic acid)的诱导体。50年来在非洲诸国用于丝虫病和锥虫病的治疗,通常有发热、急性神经障碍、过敏症及肝功能异常等副作用。体外试验表明对病毒的复制有抑制作用,对7名AIDS患者每周2克治疗6周,未见毒性反应。
In April 1985, an international conference on AIDS treatment was held in the United States. There are three types of viruses that cause AIDS, LAV associated with lymph nodes found by Montagnier, HTLV-III associated with T lymphocytes isolated by Gallo, and ARV discovered by Levy. Six anti-AIDS drugs that inhibit cell replication have been found so far. Suramin Sodium is an inducer of naphthalene trisulfonic acid. For 50 years in Africa for filariasis and trypanosomiasis treatment, usually fever, acute neurological disorders, allergies and liver dysfunction and other side effects. In vitro tests showed that the replication of the virus has an inhibitory effect on the 7 AIDS patients 2 grams per week for 6 weeks treatment, no toxic reaction.