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急性淋巴细胞白血病(ALL)发生去纤维蛋白综合征(DFS)的报告很少。本文报告成人ALL52例在诱导缓解沼疗期间,有4例发生急性DFS的临床和实验室特征及其治疗结果。此4例病人抗白皿病治疗前硫酸盐鱼精蛋白试验(PST)和乙醇胶试验(EGT)均阳性,凝血酶凝固时间(TCT)均轻度增高,纤维蛋白原降解产物(FDP)高于正常。例2、例3纤维蛋白原低于正常,除例3有轻度紫癜外,另外3例均无出血现象。但当使用细胞毒药物治疗后2～4天,出现严重出
Acute lymphoblastic leukemia (ALL) reported fibrinolytic syndrome (DFS) is rarely reported. This report reports the clinical and laboratory features of acute DFS in 4 out of 52 ALL patients who underwent induction remission and their outcomes. The four patients were positive for PST and EGT before treatment and had slightly increased thrombin clotting time (TCT) and high fibrinogen degradation product (FDP) Normal. Cases 2, 3 cases of fibrinogen below normal, except for cases 3 mild purpura, the other three cases were no bleeding. However, when using cytotoxic drugs after 2 to 4 days, a serious out