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目的:应用统计学参数图示法(SPM)分析99Tcm标记的双半胱乙酯(99Tcm-ECD)影像,探查全脑血流变化,进而阐明Parkinson病的发病机制。方法:研究对象包括28例Parkinson病患者(38～79岁)与48例健康志愿者(38～79岁)。前者按Hoehn和Yahr法分为期:、期各8例为第一组;、期分别为9例和3例
OBJECTIVE: To analyze 99Tcm-labeled 99Tcm-ECD images by means of statistical parametric mapping (SPM) to explore the changes of cerebral blood flow and elucidate the pathogenesis of Parkinson’s disease. Methods: Subjects included 28 Parkinson disease patients (38-79 years) and 48 healthy volunteers (38-79 years). The former by Hoehn and Yahr law is divided into: period of 8 cases for the first group; period of 9 cases and 3 cases