论文部分内容阅读
作者以平皿双倍稀释法测定亚胺硫霉素(TN)和氟哌酸对54株临床分离的绿脓杆菌的单独与联合抗菌活性,并与其他14种抗生素的抗菌活性作比较。所有受试的绿脓杆菌对羧苄青霉素、妥布霉素、庆大霉素和西索米星均耐药,其中47株产PSE 酶。联合药敏以分段抑菌指数(FIC)判断结果。结果表明,54株绿脓杆菌中87%的菌株对羧苄青霉素高度耐药(MIC≥1024mg/L),对庆大霉素、妥布霉素、西索米星和地贝卡星(Dibekacin)全部耐药,MIC 分刚为>64、8、16和32mg/l。亚胺硫霉素、氟哌峻和单酰胺菌素(AZ)对受试的多重耐药菌株具有
The authors tested the separate and combined antibacterial activity of amikacin (TN) and norfloxacin against 54 clinically isolated Pseudomonas aeruginosa by the double-dilution method and compared with the antibacterial activity of the other 14 antibiotics. All tested Pseudomonas aeruginosa were resistant to carbenicillin, tobramycin, gentamicin and sisomicin, of which 47 were PSE-producing. Joint susceptibility to Fragment Index (FIC) to determine the results. The results showed that 87% of the 54 strains of Pseudomonas aeruginosa were highly resistant to carbenicillin (MIC≥1024 mg / L), and were resistant to gentamicin, tobramycin, sisomicin and Dibekacin ) Were all resistant, MIC scores were> 64, 8, 16 and 32 mg / l. Imipenem, droperidol and monoammulin (AZ) had the effect on the multidrug resistant strains tested