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采用ＥＬＩＳＡ法对１９例化脓性脑膜炎（化脑）患儿进行脑液中可溶性白细胞介素２受体（ＳＩＬ－２Ｒ）测定并对部分患儿进行动态观察。结果表明，化脑患儿脑脊液中ＳＩＬ－２Ｒ的测定值明显高于对照儿的测定值（Ｐ＜０．００１），随着化脑治疗的好转与恢复，脑脊液中ＳＩＬ－２Ｒ的水平也明显下降。提示测定脑脊液中ＳＩＬ－２Ｒ有助于化脑的诊断及疗效观察。
Twenty-nine children with purulent meningitis (TB) were enrolled in this study. Soluble interleukin-2 receptor (SIL-2R) was measured in brain fluid and some of the children were observed dynamically by ELISA. The results showed that the levels of SIL-2R in cerebrospinal fluid of children with brain syndrome were significantly higher than those of the control children (P <0.001). The levels of SIL-2R in cerebrospinal fluid were also significantly increased with the improvement and recovery of brain therapy decline. Prompt determination of SIL-2R in cerebrospinal fluid is helpful to the diagnosis and therapeutic effect of brain.