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目的:评价盐酸戊乙奎醚术前全身麻醉对上呼吸道感染患儿手术围术期呼吸系统的影响。方法:选取医院2014年4月—2016年3月间收治的上肢骨折切开复位内固定术并患有上呼吸道感染患儿76例,采取双盲法将其分为对照组和观察组(每组38例);手术前30 min,对照组患者给予阿托品肌肉注射,观察组患者给予盐酸戊乙奎醚肌肉注射预防支气管和喉痉挛,比较两组患儿用药后围术期呼吸系统不良反应的发生率。结果:观察组患者用药后术中心率的平均值为(102.5±17.6)次/min明显低于对照组为(117.5±18.6)次/min(P<0.05);观察组患者吸痰大于2次的频率为13.16%低于对照组为50.00%(P<0.05),痉挛的总发生率为15.79低于对照组为36.84%(P<0.05)。结论:上肢骨折切开复位内固定术并患有上呼吸道感染患儿,采用盐酸戊乙奎醚术前全身麻醉能降低患儿心率及吸痰的频率,能有效预防患者支气管痉挛和喉痉挛的发生率。
Objective: To evaluate the effect of preoperative anesthesia of penehyclidine hydrochloride on the respiratory system during perioperative period in children with upper respiratory tract infection. Methods: Totally 76 children with upper respiratory tract infection who underwent upper extremity fracture in our hospital from April 2014 to March 2016 were divided into control group and observation group Group 38). The patients in the control group were injected intramuscularly with atropine 30 min before operation. The patients in the observation group were given intramuscular injection of penehyclidine hydrochloride to prevent bronchial and laryngospasm. The adverse reactions of respiratory system in the two groups were compared Occurrence rate. Results: The average postoperative heart rate of the observation group was (102.5 ± 17.6) times / min which was significantly lower than that of the control group (117.5 ± 18.6) times / min (P <0.05) (13.16%) was lower than that of the control group (50.00%) (P <0.05). The total incidence of spasm was 15.79, which was 36.84% lower than that of the control group (P <0.05). CONCLUSION: Open reduction and internal fixation of upper extremity fractures with upper respiratory tract infection in children. Preoperative general anesthesia with penehyclidine hydrochloride can reduce the frequency of heart rate and suctioning, which can effectively prevent bronchospasm and laryngospasm Occurrence rate.