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[目的]观察补肾益肺健脾汤联合西药治疗小儿哮喘缓解期疗效。[方法]使用随机平行对照方法,将90例门诊患者按抛硬币法简单随机分为两组。对照组45例硫酸沙丁胺醇,100~200μg/d,2次/d;异丙托溴铵,40~80μg/次,2次/d。治疗组45例补肾益肺健脾汤(肉苁蓉6g,冬虫夏草2g,党参10g,灵芝6g,白术10g,熟地6g,麦冬、补骨脂各10g,陈皮6g,五味子10g,胡桃肉研末另冲6g),1剂/d,水煎200m L,早晚分服;西药治疗同对照组。连续治疗120d为1疗程。观测临床症状、Ig G、Ig A、Ig M、不良反应。治疗1疗程,判定疗效。[结果]治疗组临床控制18例,显效15例,有效9例,无效3例,总有效率93.33%。对照组痊临床控制10例,显效12例,有效12例,无效11例,总有效率75.56%。治疗组疗效优于对照组(P<0.05)。免疫球蛋白指标两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]补肾益肺健脾汤联合西药治疗小儿哮喘缓解期疗效满意,无副作用,值得推广。
[Objective] To observe the effect of Bushen Yifei Jianpi Decoction combined with western medicine in treating pediatric asthma remission. [Methods] Using randomized parallel control method, 90 outpatients were randomly divided into two groups according to the coin tossing method. Control group, 45 cases of salbutamol sulfate, 100 ~ 200μg / d, 2 times / d, ipratropium bromide, 40 ~ 80μg / time, 2 times / d. The treatment group, 45 cases of Bushen Yifei Jianpi Tang (Cistanche 6g, Cordyceps 2g, Codonopsis 10g, Ganoderma lucidum 6g, Atractylodes 10g, Rehmannia 6g, Radix, psoralen the 10g, dried tangerine peel 6g, Schisandra 10g, 6g), 1 / d, decoction 200m L, morning and evening service; western medicine treatment with the control group. Continuous treatment of 120d for a course of treatment. Observed clinical symptoms, Ig G, Ig A, Ig M, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] In the treatment group, 18 cases were controlled clinically, 15 cases were markedly effective, 9 cases were effective and 3 cases were ineffective. The total effective rate was 93.33%. Control group recovered clinical control in 10 cases, 12 cases markedly effective in 12 cases, 11 cases were ineffective, the total effective rate was 75.56%. The treatment group was better than the control group (P <0.05). Immunoglobulin index improved in both groups (P <0.05), the treatment group improved better than the control group (P <0.05). [Conclusion] Bushen Yifei Jianpi Decoction combined with western medicine has satisfactory efficacy and no side effects in remission period of pediatric asthma, which deserves promotion.