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本文报告应用人胎肝细胞(FLC)悬液输注治疗亚急性重症肝炎及慢性重症肝炎的结果。材料及方法一、病例诊断:参照1984年(南宁)全国病毒性肝炎学术会议制订的标准,其中包括亚急性重症肝炎25例,(23例经肝穿活检病理证实2例Ⅱ度以上肝昏迷);慢性重症肝炎16例(6例肝活检证实)。两组平均年龄分别为35.9岁及38.3岁,病情相近(表1)。二、治疗方法 (一)人胎肝细胞制备:取自母亲健康、水囊引产3~6个月龄正常胎儿,在无菌室超净台内制成游离肝细胞悬液200~250ml。 (二)用法:制成肝细胞悬液,在2小时内静脉输注,每次肝细胞数为1.5~5.8×10~9,细胞存
This article reports the results of the treatment of sub-acute severe hepatitis and chronic severe hepatitis using human fetal liver cells (FLC) suspension infusion. Materials and methods First, the diagnosis of cases: With reference to the standard (1984) (Nanning) National Viral Hepatitis Symposium, including 25 cases of subacute severe hepatitis, (23 cases confirmed by liver biopsy in 2 cases of secondary hepatic coma Ⅱ) 16 cases of chronic severe hepatitis (confirmed by 6 liver biopsy). The average age of the two groups were 35.9 years and 38.3 years old, the disease is similar (Table 1). Second, the treatment (a) human fetal liver cells Preparation: taken from the mother’s health, the water bag induced abortion 3 to 6 months old normal fetus, made in the clean room clean bench free liver cell suspension 200 ~ 250ml. (B) usage: made of liver cell suspension, intravenous infusion within 2 hours, each of the number of hepatocytes 1.5 ~ 5.8 × 10 ~ 9, cell stock