论文部分内容阅读
1目的 比较奥曲肽和垂体后叶素治疗肝硬化食管胃底静脉曲张破裂出血的临床效果。 2方法 将92例 (10 5次 )食管胃底静脉曲张破裂出血病人随机分为奥曲肽组 (5 0例 5 8次 )和垂体后叶素组 (4 2例 47次 ) ,分别给予奥曲肽和垂体后叶素治疗 ,每隔 0 .5 h冲洗胃腔吸取胃液 1次 ,比较两组止血率。 3结果 奥曲肽组和垂体后叶素组 8h内止血率分别为 6 0 .3% ,17.0 % ,差异有极显著性 (χ2 =2 0 .15 ,P<0 .0 1) ;2 4h内止血率分别为 82 .7% ,6 1.7% ,差异有显著性 (χ2 =5 .89,P<0 .0 5 ) ;停药 7d内再出血率分别为 10 .3% ,12 .8% ,差异无显著性 (χ2 =0 .15 ,P>0 .0 5 )。 4结论 奥曲肽治疗食管胃底静脉曲张破裂出血止血速度及效果优于垂体后叶素
1 Objective To compare the clinical efficacy of octreotide and pituitrin in the treatment of patients with esophageal and gastric variceal bleeding due to cirrhosis. Methods 92 patients (105 times) esophagogastric variceal bleeding patients were randomly divided into octreotide group (50 cases 58) and pituitary vasopressin group (42 cases 47 times), respectively, given octreotide and pituitary Vasopressin treatment, every 0 .5 h rinse the gastric cavity to draw gastric juice 1, compare the two groups of hemostasis. 3 Results octreotide and pituitrin within 8h hemostasis rates were 60.3%, 17.0%, the difference was significant (χ2 = 20.15, P <0.01); within 24 hours of hemostasis The rates of rebleeding were 10.3% and 12.8% respectively within 7 days after drug withdrawal, with the rates of 82.7% and 67.1%, respectively (χ2 = 5.89, P <0.05) There was no significant difference (χ2 = 0.15, P> 0.05). 4 Conclusion octreotide treatment of esophageal variceal hemorrhage to stop bleeding speed and effect than pituitary vasopressin