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目的 为了探讨肾上腺皮质激素不同方法治疗淤胆型肝炎的疗效。方法 将 146例淤胆型肝炎患者分成两组 :强的松组 74例 ,地塞米松组 72例。地塞米松组用地塞米松 2 .5~ 5 mg静推 ,隔日 1次 ,4周为 1个疗程。强的松组用强的松 30~ 6 0 mg,每日 1次 ,仍以 4周为 1疗程。疗程结束时两组的疗效进行比较。结果 总有效率强的松组为77.0 % ,地塞米松组总有效率为 98.6 % ,两组比较有显著差异 P<0 .0 1。结论 地塞米松隔日疗法对淤胆型肝炎治愈率有明显提高 ,平均退黄时间缩短 ,复发率降低
Objective To investigate the efficacy of different methods of adrenal cortex hormones in treating cholestatic hepatitis. Methods 146 patients with cholestatic hepatitis were divided into two groups: 74 in prednisone group and 72 in dexamethasone group. Dexamethasone group with dexamethasone 2.5 ~ 5 mg static push, every other day, 4 weeks for a course of treatment. Prednisone prednisone 30 ~ 60mg, 1 day, still 4 weeks for a course of treatment. The efficacy of the two groups was compared at the end of the course of treatment. The results of the total effective prednisone group was 77.0%, the total effective rate of dexamethasone group was 98.6%, there was a significant difference between the two groups P <0. Conclusion Dexamethasone every other day treatment significantly improved the cure rate of cholestatic hepatitis, the average withdrawal time is shortened and the recurrence rate is reduced