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目的:研究乙型肝炎病毒表面抗原/梅毒螺旋体抗体(HBsAg/TP)联合检测试剂(胶体金法)用于献血者血液初筛的效果。方法:选择2014年5月至2016年4月,在东莞市中心血站献血的献血者为研究对象,共146953人次,其中2014年5月至2015年4月献血的为对照组(72164人次),初筛血液使用乙型肝炎试纸条,2015年5月至2016年4月献血的为观察组(74789人次),初筛血液使用HBsAg/TP联合检测试剂,比较两者乙型肝炎表面抗原和梅毒螺旋体抗体的复检阳性率。结果:使用HBsAg/TP联合检测试剂初筛血液后,乙型肝炎表面抗原阳性复检阳性率从0.67%下降至0.53%;血液因梅毒螺旋体抗体阳性而报废的从0.66%下降至0.21%,差异具有统计学意义(P<0.05)。结论:使用HBsAg/TP进行血液初筛,操作简单、可靠,能大大降低血液的报废率。
Objective: To study the effect of Hepatitis B virus surface antigen / Treponema pallidum antibody (HBsAg / TP) combined detection reagent (colloidal gold method) on the blood screening of blood donors. Methods: From May 2014 to April 2016, blood donors who donated blood in Dongguan center were selected as research objects, 146953 people were donated, among which blood donation was from May 2014 to April 2015 (72164 persons) Blood samples were collected from hepatitis B test strips, blood samples were collected from May 2015 to April 2016 (74,789), HBsAg / TP combination assay was used to screen the blood, and the hepatitis B surface antigen And Treponema pallidum antibody retest positive rate. Results: The positive rate of HBsAg positive retesting decreased from 0.67% to 0.53% after screening blood with HBsAg / TP combined detection reagent; the rate of rejection from 0.66% to 0.21% in blood decreased from 0.66% to 0.21% Statistically significant (P <0.05). Conclusion: The preliminary screening of blood using HBsAg / TP is simple and reliable, and can greatly reduce the rejection rate of blood.