论文部分内容阅读
对近两年来专利报道中三个系列２４个磷脂酶Ａ２抑制剂进行了三维构效关系的研究，采用分子场比较分析方法（ＣｏＭＦＡ）寻找结构与活性之间的关系，建立了一个可靠的构效关系模型，为活性分子的进一步修饰和改造提供了信息。
In the recent two years, three series of 24 phospholipase A2 inhibitors were reported in the patent reports, and the relationship between structure and activity was searched by molecular field comparative analysis (CoMFA) to establish a reliable structure Efficient model for the further modification and modification of active molecules provides information.