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目的探讨米非司酮治疗更年期功能性子宫出血的疗效。方法选取2009年3月至2011年10月我院收治的54例更年期功能性子宫出血患者为研究对象,所有病例均给予米非司酮治疗,疗程为3个月,观察治疗后疗效。结果患者治疗后FSH、E2、LH和P水平均较治疗前有显著下降(P<0.05);治疗后患者子宫内膜厚度较治疗前明显下降,血红蛋白浓度显著高于治疗前水平,差异均有统计学意义(P<0.05)。结论米非司酮治疗更年期功能性子宫出血临床疗效确切,且不良反应较轻,值得推广应用。
Objective To investigate the efficacy of mifepristone in the treatment of climacteric functional uterine bleeding. Methods From March 2009 to October 2011, 54 cases of menopausal dysfunctional uterine bleeding were treated in our hospital. All patients were treated with mifepristone. The course of treatment was 3 months and the therapeutic effect was observed. Results The levels of FSH, E2, LH and P in patients after treatment were significantly lower than those before treatment (P <0.05). The thickness of endometrium in patients after treatment was significantly lower than that before treatment, and the hemoglobin concentration was significantly higher than that before treatment Statistical significance (P <0.05). Conclusion The efficacy of mifepristone in treatment of climacteric functional uterine bleeding is definite and the side effects are mild. It is worth popularizing and applying.