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在人类寄生虫病中,肠道线虫—蛔虫、钩虫、蛲虫和鞭虫等的感染极为普遍。应用药物积极治疗病人和感染者,不仅对恢复病人健康、保护劳动力,而且对控制或消灭传染源都有重要的现实意义。我国应用植物药驱虫的历史相当悠久,如用土荆芥油、山道年、使君子及苦楝根皮等均可取得一定驱虫效果。而且还作了有效成分分析,象土荆芥油的驱蛔脑、使君子的使君子钾、苦楝树皮的川楝素等,都是我国的研究成果。但这些药物的疗效不够理想,副作用有的较大,因此在使用上受到限制。合成药方面,过去生产的麝香草酚、四氯化碳、己雷锁辛、四氯乙烯、1-溴-2荼酚、次苯基二异硫氰酸盐等,亦因效果或毒性问题遂被少用或淘汰。随着研究工作的进展,将目前的驱肠道线虫药物,按药物的化学组成分述如下:
In human parasitic diseases, gut nematodes - roundworms, hookworms, pinworms and whipworms are extremely common infections. Active drug treatment of patients and infected patients, not only to restore patient health, protect the workforce, but also to control or eliminate sources of infection have important practical significance. Herbal insecticides have a long history of application in China. Herbicides, such as catmint oil, hill year, gentleman and neem root bark, can achieve certain deworming effect. But also made an active ingredient analysis, such as earthworm catfish oil drive roundworm brain so gentle gentleman potassium, neem bark toosendanin, etc., are our research results. However, the efficacy of these drugs is not ideal, some of the larger side effects, it is limited in use. Synthetic drugs, the past production of thymol, carbon tetrachloride, hexamiloxin, tetrachlorethylene, 1-bromo-2 phenol, phenylenediisothiocyanate, but also because of the effect or toxicity Was less used or eliminated. With the progress of research work, the current drug-resistant nematode drug, according to the chemical composition of the drug as follows: