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目的:观察雷米普利联合吲达帕胺对原发性高血压患者血压的影响。方法:165例原发性高血压患者随机分为联合应用雷米普利与吲达帕胺组(A组)、雷米普利组(B组)、吲达帕胺组(C组),治疗期间采用临床常规方法观察病情,每天早晨测血压、心率1次,治疗前及疗程结束后均进行常规检查等。结果:联合用药可以有效降低血压,A组与B组、C组比较有统计学差异(P<0.05),三组治疗后与治疗前比较也有统计学差异(P<0.05)。结论:联合使用雷米普利和吲达帕胺与单独使用雷米普利、吲达帕胺可以有效的控制原发性高血压患者的血压,但两者联合降压疗效优于单独使用雷米普利或吲达帕胺。
Objective: To observe the effect of ramipril combined with indapamide on blood pressure in patients with essential hypertension. Methods: A total of 165 patients with essential hypertension were randomly divided into three groups: ramipril combined with indapamide (group A), ramipril (group B), indapamide (group C) During treatment, clinical routine methods were used to observe the condition. Blood pressure and heart rate were measured every morning, and routine examination was performed before treatment and after treatment. Results: The combination therapy can effectively reduce the blood pressure. There was a significant difference between group A and group B and group C (P <0.05). There was also significant difference between the three groups before and after treatment (P <0.05). Conclusion: The combination of ramipril and indapamide and ramipril and indapamide can effectively control the blood pressure in patients with essential hypertension, but the combination of ramipril and indapamide is better than ramie alone Pulimy or indapamide.