论文部分内容阅读
胆红素由血红蛋白分解而来,是血红素的代谢产物,即血红素的卟啉环裂解后放出铁,成为直线型4吡咯的结构。血红素Ⅸ→胆绿素Ⅸ_a→胆红素Ⅸ_a 除了血红蛋白外,胆红素也可以从肌红蛋白、细胞色素、过氧化氢酶、过氧化物酶、色氨酸吡咯酶等裂解而来,正常人每天产生350～400毫克胆红素,其中2/3(65％)来自血红蛋白,1/3来自其它方面,特别来自肝脏,人体所有细胞,包括肝、脑、脾、成纤维细胞均可合成与裂解血红素,产生胆红素。肝、脾的细胞含裂解血红素的酶最多,产生的胆红素也较其它脏器为多。
Bilirubin from the decomposition of hemoglobin, heme is the metabolite, that heme protoporphyrin ring release of iron, a linear 4 pyrrole structure. Heme Ⅸ → biliverdin Ⅸ_a → bilirubin Ⅸ b In addition to hemoglobin, bilirubin can also be cleaved from myoglobin, cytochrome, catalase, peroxidase, tryptophan and pyrrolizidine, Normal people produce 350 to 400 milligrams of bilirubin per day, of which 2/3 (65%) from hemoglobin and 1/3 from other sources, especially from the liver, all human cells, including liver, brain, spleen and fibroblasts Synthesis and cleavage of heme, produce bilirubin. Liver, spleen cells contain the most hemicellulose lytic enzymes, bilirubin also produced more than other organs.