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宫颈癌是威胁女性健康、导致死亡的主要恶性肿瘤之一。人乳头状瘤病毒(HPV)感染是宫颈癌发生的必要条件。本文对宫颈癌的病因、HPV的分子结构、特性和分型、HPV感染和宫颈癌的关系、HPV发病机制、HPV整合状态的检测及意义、HPV的检测方法和意义、HPV的感染率和型别分布以及HPV疫苗的现状和前景进行总结,并加以介绍。
Cervical cancer is one of the major malignant tumors that threaten the health of women and cause death. Human papilloma virus (HPV) infection is a necessary condition for cervical cancer. In this paper, the etiology of cervical cancer, the molecular structure, characteristics and typing of HPV, the relationship between HPV infection and cervical cancer, the pathogenesis of HPV, the detection and significance of HPV integration status, the detection method and significance of HPV, the HPV infection rate and type Do not distribute and HPV vaccine status and prospects are summarized and introduced.