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大肠癌肝转移的发生率较高,是治疗失败的主要原因之一,据美国的资料,美国每年新发生大肠癌130,000例,死亡59,000例,其中大约有40,000死于肝转移。六十年代Woodington破除了传统的观点,对转移性肝癌采取外科手术治疗,25例平均生存期35.1月,5年生存率20％。七十年代美国Mayo Clinic和Sloan Kettering癌症纪念中心等发现在转移性肝癌的手术治疗中,来源于大肠癌肝转移治疗效果最好,其结果令人鼓舞。八十年代以来此领域研究更为活跃,文献积累大肠癌肝转移手术治疗的病例已超过千
The high incidence of hepatic metastases of colorectal cancer is one of the main reasons for treatment failure. According to the United States, 130,000 new cases of colorectal cancer and 59,000 deaths occur each year in the United States, of which approximately 40,000 died of liver metastases. In the 1960s, Woodington dismissed the traditional view of surgical treatment of metastatic liver cancer. The average survival time of 25 patients was 35.1 months, and the 5-year survival rate was 20%. In the 1970s, Mayo Clinic and Sloan Kettering Cancer Memorial Center in the United States found that liver metastases derived from colorectal cancer have the best results in the surgical treatment of metastatic liver cancer. The results are encouraging. Research in this field has been more active since the 1980s, and there have been more than 1,000 cases of documented liver metastases for colorectal cancer.