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目的:报告我科1986年7月～1996年7月经蝶显微手术治疗垂体腺瘤360例.女性233例.男性127冽:年龄13～66岁、平均38.6岁.其中大腺瘤143例(39.7%).微腺癌217例(603%).方法:均经CT扫描或MRI确诊.手术采取经唇下-鼻中隔-蝶窦入路或经鼻前庭-蝶窦人路两种方式行肿瘤切除术.结果:术目无死亡.296例获长期随访(平均3.5年).246例(83.1%)恢复良好.50例(16.9%)肿瘤有复发,需行再次手术、或采用药物、放疗或放射外科治疗.结论:垂体腺瘤采取经蝶显微外科治疗是一种安全、有效的方法.
OBJECTIVE: To report 360 cases of pituitary adenoma treated by butterfly microsurgery in our department from July 1986 to July 1996. There were 233 females and 127 males: aged 13 to 66 years and mean 38.6 years. Among them, 143 cases of large adenomas ( 39.7%). 217 cases of microadenocarcinoma (603%). Methods: All patients were diagnosed by CT scan or MRI. The operation was performed by sub-labial-nasal septum-sphenoid sinus approach or nasal vestibular-sphenoid sinus approach. Resection. Results: There were no deaths in the procedure. 296 cases were followed for a long period of time (3.5 years on average). 246 cases (83.1%) recovered well. 50 cases (16.9%) had tumor recurrence and needed reoperation or medication or radiotherapy. Or radiosurgery. Conclusion: Transsphenoidal microsurgical treatment of pituitary adenomas is a safe and effective method.