Quercetin Attenuates Benzo（α）pyrene-induced CYP1A Expression

• 作 者: Perepechaeva ML Seredina TA Si
• 机 构: InstituteofMolecularBiologvandBiophysics,FederalresearchcenterInstituteofCytologyandGenetics,Novosib
• 出 处: 生物医学与环境科学：英文版
• 发表日期: 2017年4期
• 基金项目: This work was supported by the Russian Foundation for Basic Research （project No. 05-04-48327-a）, and a grant from the Presidium of RAS ＇Molecular and Cellular Biology＇.

<正>We studied effects of nutrient quercetin on cytochromes’Р450 1А(CYP1A)activities(measured spectrofluorimetrically using 7-ethoxy-resorufin for CYP1A1 and 7-methoxy-resorufin for CYP1A2 as substrates),on mR NA levels(measured by RT-PCR),and on DNA