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目的探讨抗幽门螺杆菌(Hp)治疗在特发性血小板减少性紫癜(ITP)治疗中的作用。方法将54例Hp阳性的ITP患者随机分为治疗组和对照组,治疗组给予Hp根治治疗,观察两组的治疗疗效。结果治疗组ITP治疗有效率为88.9%,对照组为74.1%,两组比较差异有统计学意义(P<0.05)。治疗组ITP复发率为11.1%,而对照组为55.6%,两组比较,差异有统计学意义(P<0.05)。结论Hp感染可能是ITP的发病原因之一,抗Hp治疗是Hp阳性的ITP患者的常规治疗方法。
Objective To investigate the role of anti-Helicobacter pylori (Hp) in the treatment of idiopathic thrombocytopenic purpura (ITP). Methods 54 cases of Hp positive ITP patients were randomly divided into treatment group and control group. The treatment group was given Hp radical therapy and the curative effect of the two groups was observed. Results The effective rate of ITP treatment was 88.9% in the treatment group and 74.1% in the control group, with significant difference between the two groups (P <0.05). The recurrence rate of ITP in the treatment group was 11.1%, compared with 55.6% in the control group, the difference was statistically significant (P <0.05). Conclusion Hp infection may be one of the causes of ITP. Anti-Hp therapy is a common treatment for Hp-positive ITP patients.