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目的了解山东省某儿童医院麻疹疑似病例的血清学检测情况,为麻疹的监测与预防提供依据。方法分析2014年6月至2017年5月山东省某儿童医院就诊麻疹疑似病例2 122份血标本的检测结果。结果 2 122例麻疹疑似患儿血清学检测阳性率为38.17%(810例)。男童阳性率为67.31%(527/783),女童为21.14%(283/1 339)(P<0.01)。2015年冬季和2016年春季共检出麻疹血清学阳性587例,占3年阳性总数的72.47%。810例阳性患者中,<1岁检出麻疹IgM抗体阳性521例,占阳性标本总数的64.32%。初诊科室为感染性疾病科患者占47.16%(382例)。结论2014年6月至2017年5月山东省某儿童医院麻疹疑似病例血清学检测显示,男童和<1岁年龄阳性率高。
Objective To understand the serological detection of suspected cases of measles in a children’s hospital in Shandong Province and provide the basis for the monitoring and prevention of measles. Methods The data of 2 122 blood samples from suspected measles cases in a children’s hospital in Shandong Province from June 2014 to May 2017 were analyzed. Results The positive rate of serological test in 2 122 measles children was 38.17% (810 cases). The positive rate of boys was 67.31% (527/783) and that of girls was 21.14% (283/1 339) (P <0.01). Measles seropositivity was detected in 587 cases in winter 2015 and spring 2016, accounting for 72.47% of the total positive cases in 3 years. Of the 810 positive patients, measles IgM antibodies were detected in 521 cases at <1 year old, accounting for 64.32% of the total positive samples. Newly diagnosed departments of infectious diseases accounted for 47.16% (382 cases). Conclusions Serum tests of suspected cases of measles in a children’s hospital in Shandong Province from June 2014 to May 2017 showed that boys and children <1 year old had a high positive rate.