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目的:观察理气止痛方治疗小儿脾虚夹积型肠系膜淋巴结炎的临床疗效。方法:将64例脾虚夹积型肠系膜淋巴结炎患儿随机分为治疗组和对照组,每组32例。治疗组采用理气止痛方治疗,对照组采用四磨汤口服液治疗,疗程为4周。评价两组的临床疗效,比较两组患儿的中医证候积分、腹痛消失时间及肿大淋巴结的纵径、横径。结果:治疗后,治疗组和对照组的总有效率分别为90.0%和66.7%,两组临床疗效比较,差异有统计学意义(P<0.05);两组患儿的中医证候积分均显著降低(P<0.05),且治疗组患儿的积分低于对照组(P<0.05);两组患儿的肿大淋巴结纵径、横径均显著回缩(P<0.05),且治疗组患儿的肿大淋巴结纵径、横径短于对照组(P<0.05)。治疗组患儿的腹痛消失时间较对照组明显缩短(P<0.05)。结论:理气止痛方治疗脾虚夹积型小儿肠系膜淋巴结炎具有较好的疗效,可有效改善患儿的临床症状,缩小肿大淋巴结。
Objective: To observe the clinical curative effect of “Qi” and “Zhitong Recipe” in treating infantile splenic syndrome mesenteric lymphadenitis. Methods: Sixty-four children with splenic syndrome of mesenteric lymphadenitis were randomly divided into treatment group and control group, with 32 cases in each group. The treatment group was treated with qi and relieving pain, while the control group was treated with Siu Tang decoction for 4 weeks. The clinical efficacy of the two groups were evaluated. The TCM syndrome scores, the disappearance of abdominal pain and the longitudinal and transverse diameters of the enlarged lymph nodes were compared between the two groups. Results: After treatment, the total effective rates of the treatment group and the control group were 90.0% and 66.7%, respectively. There was significant difference between the two groups in clinical curative effect (P <0.05). The scores of TCM syndromes in both groups were significant (P <0.05), and the scores of children in the treatment group were lower than those in the control group (P <0.05). The longitudinal and transverse diameters of the enlarged lymph nodes in both groups were significantly reduced (P <0.05) Children with enlarged lymph nodes longitudinal diameter, transverse diameter shorter than the control group (P <0.05). The disappearance time of abdominal pain in treatment group was significantly shorter than that in control group (P <0.05). CONCLUSION: Liqi Zhitong Recipe has good curative effect in treatment of children with mesenteric lymphadenitis with splenic syndrome, which can effectively improve the clinical symptoms and reduce the enlarged lymph nodes.