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目的:观察乳酸菌联合倍美力软膏、甲硝唑栓治疗萎缩性阴道炎的临床疗效。方法:将138例萎缩性阴道炎患者随机分为研究组(70例)和对照组(68例)。对照组给予倍美力软膏、甲硝唑栓治疗,研究组另加用乳酸菌治疗。10天为1疗程,治疗结束后观察两组的临床疗效,并于3个月、6个月随诊,分别统计两组复发情况予以比较分析。结果:研究组痊愈率和总有效率分别为68.57%和95.71%,明显高于对照组的33.82%和80.88%,差异极其显著(P<0.01)。治疗后3个月和6个月进行随访复诊,3个月复发率研究组为1.43%,对照组为32.35%,差异极其显著(P<0.01);6个月复发率研究组和对照组分别为37.14%和42.65%,差异无统计学意义(P>0.05)。结论:乳酸菌联合倍美力软膏、甲硝唑栓治疗萎缩性阴道炎具有高有效率和短期低复发率,其临床疗效较传统治疗方法有着明显的优势,值得临床推广。
Objective: To observe the clinical efficacy of lactic acid bacteria combined with Beimei Li ointment and metronidazole suppository in the treatment of atrophic vaginitis. Methods: 138 cases of atrophic vaginitis were randomly divided into study group (70 cases) and control group (68 cases). The control group was given Beimei ointment, metronidazole suppository treatment, the study group plus lactic acid bacteria treatment. 10 days for a course of treatment, the clinical efficacy of the two groups were observed after treatment, and at 3 months, 6 months follow-up, respectively, statistics of the two groups were compared recurrence. Results: The cure rate and total effective rate of the study group were 68.57% and 95.71%, respectively, which were significantly higher than that of the control group (33.82% and 80.88%, P <0.01). The 3-month and 6-month follow-up visits showed that the 3-month recurrence rate was 1.43% in the study group and 32.35% in the control group, with a significant difference (P <0.01). The 6-month recurrence rate was significantly higher in the study group and the control group 37.14% and 42.65%, respectively, with no significant difference (P> 0.05). Conclusions: Lactobacillus combined with Beimei Li ointment and metronidazole suppository have a high effective rate and a short-term low recurrence rate in treating atrophic vaginitis. The clinical efficacy is obviously superior to the traditional treatment and is worthy of clinical promotion.