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目的探讨肝病患者和供血员血清中抗HGV检测的意义。方法采用北京医科大学肝病研究所生产的试剂盒,对226例肝病患者和187例献血员血清中抗HGV进行检测。结果急性肝炎、慢性活动性肝炎、慢性迁延性肝炎、肝硬化、重型肝炎病人抗HGV阳性检出率分别为6.9%(3/43),17.9%(19/106),14.2%(5/35),33.3%(3/9)和9.1%(3.33)。肝硬化患者血清中抗HGV的检出阳性率明显高于其它各型肝炎(P<0.05)。187例献血人员中检出抗HGV4例(2.1%)。结论作者认为在供血人员中对HGV进行筛选,以避免和减少输血后肝炎的发生。
Objective To investigate the significance of anti-HGV detection in serum of patients with liver diseases and blood donors. Methods Using the kit produced by Institute of Hepatology, Beijing Medical University, anti-HGV in serum of 226 patients with liver disease and 187 blood donors was detected. Results The positive rates of anti-HGV in acute hepatitis, chronic active hepatitis, chronic persistent hepatitis, cirrhosis and severe hepatitis were 6.9% (3/43), 17.9% (19/106), 14 .2% (5/35), 33.3% (3/9) and 9.1% (3.33). The positive rate of anti-HGV in patients with cirrhosis was significantly higher than that of other types of hepatitis (P <0.05). 187 cases of blood donors were detected in anti-HGV 4 cases (2.1%). Conclusion The authors believe that HGV screening in blood donors to avoid and reduce post-transfusion hepatitis.