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美国科学家经过10年的研究,第一次人工制造出人体细胞中携带基因编码的染色体。美国俄亥俄州凯斯西部大学的基因学家维拉尔德解释说:“我们的目标是制造小的不能再小但能起作用的染色体,我们提取了染色体中我们认为发挥主要功能的部分,同我们希望研究的基因进行融合或是聚合,得到大小只有普通人体染色体1/10的人工染色体;我们把它注入到细胞中去,证明它能像人体染色体一样发挥作用。”这项研究成果为基因治疗开辟了新的途径,将来可能用来修复功能失调的染色体,甚至完全代替失调的染色体。不正常的染色体会导致某些功能紊乱,科研人员一直试图通过注入健康人体基因的方法来治疗这些紊乱。一般是利用某种媒介通过注射或吸入方式
After 10 years of research, American scientists made the first human-made generation of chromosomes carrying the genes in human cells. Willard, a geneticist at Case Western University in Ohio, USA, explains: “Our goal is to make small, but functional, chromosomes, and we extract parts of the chromosome that we think play a major role, Fusion or aggregation with the gene we want to study gives an artificial chromosome about 1/10 the size of an ordinary human chromosome; we inject it into the cell to prove it works like a human chromosome. ”" The results of this research It opens up new avenues for gene therapy, which may in the future be used to repair dysfunctional chromosomes and even completely replace the unregulated chromosomes. Abnormal chromosomes can cause some dysfunction, and researchers have been trying to treat these disorders by injecting healthy human genes. Generally use a medium by injection or inhalation