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目的:探讨抗抑郁药物对治疗胃食管反流病(GERD)的疗效。方法:选取2015年8月至2016年2月吴川市人民医院GERD的患者80例,以抽签方式分成两组,每组40例。观察组采用兰索拉唑、莫沙必利与黛力新联合治疗,对照组采用兰索拉唑、莫沙必利与安定联合治疗。比较两组患者的治疗效果。结果:使用黛力新的观察组的总有效率75.00%明显高于对照组66.67%,差异具有统计学意义(P<0.05)。结论:联合抗抑郁药治疗对老年顽固性GERD是明显有效的。
Objective: To investigate the efficacy of antidepressants in the treatment of gastroesophageal reflux disease (GERD). Methods: Eighty patients with GERD at Wuchuan People’s Hospital from August 2015 to February 2016 were selected and randomly divided into two groups (n = 40 in each group). The observation group treated with lansoprazole, mosapride and Deanxit, the control group treated with lansoprazole, mosapride and diazepam. The treatment effect of two groups of patients was compared. Results: The total effective rate of Deanxit in the observation group was 75.00%, which was significantly higher than that in the control group (66.67%), the difference was statistically significant (P <0.05). Conclusions: Combination antidepressants are effective for elderly intractable GERD.