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新制易黄丸是治疗慢性盆腔炎的经验方,临床应用取得良好效果。为了验证其药理作用,我们选用苯酚胶浆致大鼠子宫内膜炎进行实验研究,结果血液流变学包括全血比粘度、红细胞压积、血浆比粘度均有显著性改变(P<005)、血清TXB2含量升高(P<005)、6—Keto—PGF1α含量下降(P<005)。提示:新制易黄丸具有改变血液流变性,改善微循环,促进炎性病灶消退的作用。
Xinyi Yihuang Pills is a prescription for the treatment of chronic pelvic inflammatory disease. Clinical application has achieved good results. In order to verify its pharmacological effects, we used phenolic glue to induce endometritis in rats. The results showed that the hemorheology including whole blood specific viscosity, hematocrit, and plasma specific viscosity all had significant changes (P<0). 05) Serum TXB2 levels increased (P<005) and 6-Keto-PGF1α levels decreased (P<005). Tip: The new system Yihuangwan has the effect of changing the blood rheology, improving the microcirculation and promoting the regression of inflammatory lesions.