gp78 is a membrane-anchored ubiquitin ligase mediating the degradation of HMG-CoA reductase (HMGCR) and Insig-1.As a rate-limiting enzyme in cholesterol biosynt
Adipose tissue inflammation is emerging as a pathogenic link between obesity and metabolic disease.Chronic activation of the innate immune system in obese fat t
Single nucleotide polymorphisms (SNPs) represent one kind of genomic DNA variation in a population.Correspondingly, Single amino-acid polymorphisms (SAPs) deriv