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目的:探讨肌钙蛋白I(cTnI)、钠尿肽(BNP)联合诊断在早期急性心肌梗死(AMI)诊断中的作用。方法:收集胸痛发作时间在3小时以内的急诊患者120例,按AMI诊断标准分为急性心肌梗死组(AMI组)和非急性心肌梗死组,比较两组间血清BNP和cTnI水平及联合检测与单独检测的敏感性和特异度。结果:两组间血清BNP和cTnI水平,AMI组明显高于非AMI组,联合检测的敏感性和特异度均高于单独检测。结论:AMI患者在发病3小时内血清cTnI及BNP水平明显升高且联合检测有助于AMI的早期诊断。
Objective: To investigate the combined effect of cTnI and BNP in the diagnosis of early acute myocardial infarction (AMI). Methods: A total of 120 emergency patients with chest pain onset within 3 hours were divided into acute myocardial infarction group (AMI group) and non-acute myocardial infarction group according to AMI diagnostic criteria. Serum levels of BNP and cTnI were compared between the two groups, Sensitivity and specificity of individual tests. Results: The levels of serum BNP and cTnI in the two groups were significantly higher than those in the non-AMI group in AMI group. The sensitivity and specificity of combined detection were higher than those of the single group. Conclusion: The levels of serum cTnI and BNP in patients with AMI are significantly increased within 3 hours of onset and the combined detection of AMI is helpful for the early diagnosis of AMI.