The role of central nervous system on hypoglycemia and the feasibility of the brain theory in tradit

• 作 者: Hai-li Jiang Jing-jing Niu Wei-fei Zhang Wen-jin Huang Ming-yue Zhou Wen-jun Sha Jun-yan Li Fu-feng Li Ting Zhu Xin Xia Jun Zhang Yuan-dong Shen Li-gang Zhou
• 机 构: Department of Endocrinology,Shanghai Pudong Hospital,Fudan University Pudong Medical Center,Departme
• 出 处: Journal of Integrative Medicine
• 发表日期: 2014年01期
• 关键词: neuropathy homeostasis glucagon secretion protective insight clarify dependency

The central nervous system(CNS) plays a key regulatory role in glucose homeostasis.In particular,the brain is important in initiating and coordinating protective counterregulatory responses when blood glucose levels fall.This may due to the metabolic dependency of the CNS on glucose,and protection of food supply to the brain.In healthy subjects,blood glucose is normally maintained within a relatively narrow range.Hypoglycemia in diabetic patients can increase the risk of complications,such as heart disease and diabetic peripheral neuropathy.The clinical research finds that the use of traditional Chinese medicine(TCM) has a positive effect on the treatment of hypoglycemia.Here the authors reviewed the current understanding of sensing and counterregulatory responses to hypoglycemia,and discuss combining traditional Chinese and Western medicine and the theory of iatrogenic hypoglycemia in diabetes treatment.Furthermore,the authors clarify the feasibility of treating hypoglycemia on the basis of TCM theory and CNS and have an insight on its clinical practice.

The central nervous system (CNS) plays a key regulatory role in glucose homeostasis. In particular, the brain is important in initiating and coordinating protective counterregulatory responses when blood glucose levels fall. This may due to the metabolic dependency of the CNS on glucose, and protection of food supply to the brain.In healthy subjects, blood glucose is normally maintained within a relatively narrow range. Hypoglycemia in diabetic patients can increase the risk of complications, such as heart disease and diabetic peripheral neuropathy.The clinical research finds that the use of traditional Chinese medicine (TCM) has a positive effect on the treatment of hypoglycemia. Here the authors reviewed the current understanding of sensing and counterregulatory responses to hypoglycemia, and discussitary traditional Chinese and Western medicine and the theory of iatrogenic hypoglycemia in diabetes treatment. Furthermore, the authors clarify the feasibility of treating hypoglycemia on the ba sis of TCM theory and CNS and have an insight on its clinical practice.