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研究发现NDRG2具有多方面的抑癌作用,然而其背后的确切机制我们却知之甚少,经典的信号通路PI3K/AKT与肿瘤的发生发展有密切关系,了解NDRG2与PI3K/AKT信号通路的关系,可为进一步探究NDRG2的抑癌机制提供线索和思路。
However, the exact mechanism behind this phenomenon is poorly understood. The classical PI3K / AKT signaling pathway is closely related to the development and progression of tumors. Understanding the relationship between NDRG2 and PI3K / AKT signaling pathways, It can provide clues and ideas for further exploring the tumor suppressor mechanism of NDRG2.