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目的 了解复方炔诺酮治疗功能性子宫出血(功血)的疗效。方法选择2005~2009年来我站就诊的功能性子宫出血患者250例,随机分为两组,其中一组为复方炔诺酮组150例,另一组为传统疗法组(根据不同类型功血选用不同的性激素或雌-孕激素、孕-雌激素的序贯疗法)100例。随访观察2个月~2年不等。结果使用两种方法治疗功血均有效,但使用复方炔诺酮疗效更佳,疗程更短,使用简单、方便、价格便宜,服药2~6个月治愈52%,6月~1年治愈占27.3%,1~2年治愈占15.3%,疗效欠佳占5.3%。传统的治疗方法繁琐、复杂、副作用大,2~6个月治愈占38%,6月~1年治愈占21%,1~2年治愈占27%,疗效欠佳占14%。结论使用复方炔诺酮治疗功能性子宫出血疗效佳,副作用少,价廉,简单易行,基层值得推广。
Objective To understand the efficacy of compound norethindrone in the treatment of functional uterine bleeding (dysfunctional uterine bleeding). Methods A total of 250 functional dysfunctional uterine bleeding patients from 2005 to 2009 were selected and divided into two groups randomly. One group was 150 cases of compound norethisterone group and the other was conventional therapy group 100 different sex hormones or estrogen-progesterone, sequential pregnancy-estrogen therapy). Follow-up observation of 2 months to 2 years. The results of the two methods are effective in treating dysfunctional uterine bleeding, but the use of compound norethisterone is more effective, shorter course of treatment, easy to use, convenient, cheap, medication 2 to 6 months to cure 52%, 6 months to 1 year cure accounted 27.3%, 1 to 2 years to cure 15.3%, poor efficacy accounted for 5.3%. Traditional curative methods are cumbersome, complex and have a large side effect. 38% are cured in 2 to 6 months, 21% are cured in June to 1 year, 27% are cured in 1 to 2 years, and 14% are ineffective in treatment. Conclusions The use of compound norethindrone in the treatment of functional uterine bleeding with good curative effect, less side effects, low cost, simple and easy to implement, and the grassroots should be popularized.