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血栓性血小板减少性紫癜(TTP)的特点是:(1) 微血管病性溶血性贫血;(2) 血小板减少;(3) 神经症状时隐时现;(4) 发热;(5) 肾功能损害。本文就TTP的发病机理和治疗概述如下: 病变和发病机理TTP的基本病变为广泛玻璃样微血栓所致的小血管闭塞。该血栓的主要成分是血小板,也含有少量纤维蛋白。形成血栓的主要原因是血管壁的病变。这种血栓遍及周身,尤其多见于脑和肾。引起血管病变的原因可能是某种毒素所引起的小血管炎、药物变态反应,免疫复合物的沉着、全身性Shwarzman反应、
Thrombotic thrombocytopenic purpura (TTP) is characterized by: (1) microangiopathic hemolytic anemia; (2) thrombocytopenia; (3) neurological symptoms hidden; (4) fever; (5) renal dysfunction . In this paper, the pathogenesis and treatment of TTP are summarized as follows: Lesions and pathogenesis The basic lesion of TTP is the occlusion of small vessels caused by extensive glass-like micro-thrombosis. The thrombosis is the main component of platelets, also contains a small amount of fibrin. Thrombosis is the main reason for the wall of the vessel lesions. This thrombus throughout the body, especially more common in the brain and kidney. Vascular lesions may be caused by a toxin caused by small vasculitis, drug allergy, immune complex deposition, systemic Shwarzman reaction,