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目的:探讨降钙素原在早期恶性肿瘤并发感染患者中的鉴别诊断的应用价值。方法:随机选取67例恶性肿瘤感染患者和67例未发生感染的恶性肿瘤患者纳入研究对象,采用荧光免疫分析法检测血清中降钙素原(PCT)和C反应蛋白(CRP)水平。结果:感染组PCT、CRP水平均显著高于未感染组,比较差异有统计学意义(t=23.965、75.578,P<0.05);感染组检测PCT阴性分布率明显低于未感染组,PCT阳性分布率显著高于未感染组(P<0.05)。结论:降钙素原可作为恶性肿瘤并发感染患者鉴别诊断的有效指标之一,对临床早期识别、诊断、评估恶性肿瘤感染及其严重程度有重要的意义。
Objective: To investigate the value of procalcitonin in the differential diagnosis of early malignant tumor complicated with infection. Methods: Sixty-seven patients with malignant tumor and 67 patients with non-infected malignant tumor were enrolled in the study randomly. Serum procalcitonin (PCT) and C-reactive protein (CRP) levels were measured by fluorescence immunoassay. Results: The levels of PCT and CRP in the infected group were significantly higher than those in the uninfected group (t = 23.965, 75.578, P <0.05). The prevalence of PCT negative in the infected group was significantly lower than that in the non-infected group Distribution rate was significantly higher than the non-infected group (P <0.05). CONCLUSION: Procalcitonin can be used as one of the effective markers in the differential diagnosis of patients with malignant neoplasms. It is of great significance for the early identification, diagnosis, assessment of malignant tumor infection and its severity.