论文部分内容阅读
目的:建立近中移动大鼠第一磨牙的实验动物模型。方法:选用40只8周龄雌性SPF级Wistar大鼠,随机分为2组,2组均以2颗上颌切牙为支抗,近中移动上颌第一磨牙,其中一组采用传统矫治装置以结扎丝固定牵引磨牙,另一组采用硅橡胶,取模后制作个体化矫治装置固定牵引磨牙,分别比较2种方法第一磨牙近中移动距离、矫治装置脱落率及第一磨牙牙周情况,采用SPSS11.0软件包对数据进行统计学分析。结果:2组第一磨牙近中移动的距离之间无显著差异(P>0.05);而矫治装置脱落率及第一磨牙牙周情况在2组间存在显著差异,个体化矫治装置组矫治装置脱落率为5%,传统矫治装置组矫治装置脱落率为35%(P<0.05),个体化矫治装置组明显优于传统矫治装置组。结论:个体化矫治装置更适用于大鼠正畸牙移动,所建立的实验动物模型可用于今后大鼠牙移动的相关实验研究。
OBJECTIVE: To establish a model animal model of the first molars in near-mid-moving rats. Methods: Forty eight-week-old Wistar female SPF rats were randomly divided into two groups. Two maxillary incisors were used as the anchorage in the two groups. The maxillary first molar was moved proximally and in one group, Silk fixed traction molars, the other group using silicone rubber, making the model after the individual correction device fixed traction molars, respectively, two methods of first molars moving distance, correction device and the first molar periodontal situation, the use of SPSS11 .0 Software package for statistical analysis of data. Results: There was no significant difference in the distance between the first molars and the second molars in the two groups (P> 0.05). However, there was a significant difference between the two groups in the rate of removal of the orthodontic appliance and the periodontal status of the first molars. Rate of 5%, the traditional orthodontic device treatment device shedding rate was 35% (P <0.05), the individual correction device group was significantly better than the traditional correction device group. Conclusion: The individual appliance is more suitable for the orthodontic tooth movement in rats. The experimental animal model established can be used for the related experimental research on tooth movement in rats.