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1994—1997年在感染率＞15％的流行村进行为期4年的吡喹酮隔年普治（A组）和每年普治（B组）对照试验显示，A组人群感染率下降78．23％，耕牛感染率下降63．61％，人群EPG下降79．90％；B组分别下降77．69％、46．40％和92．84％。两组粪检阳性者的B型超声波图像干预前后无显著性差异。两组效果相当，但是A组费用仅为B组的1／2。对于经济欠发达的高度流行区，用吡喹酮隔年普治1次是一种既能有效控制血吸虫病，又能低成本长期运作的防治手段。
A four-year praziquantel every year between 1994 and 1997 in the endemic villages with a prevalence of> 15% (group A) and annual Prussian (group B) control trial showed that the infection rate in group A fell by 78.23% , The cattle infection rate decreased 63.61%, the population EPG decreased 79.90%; B group decreased 77.69%, 46.40% and 92.84%. There was no significant difference between the two groups of B-mode ultrasound images before and after the intervention. The two groups have the same effect, but the cost of group A is only 1/2 of that of group B. For economically underdeveloped areas of high prevalence, praziquantel every other year of 普治 once is an effective control of schistosomiasis, but also low-cost long-term operation of the prevention and control measures.