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目的探讨孕24周前多囊卵巢综合征(PCOS)孕妇体重增加与妊娠期糖尿病(GDM)间的关系。方法选取在我院产科门诊定期产检的PCOS孕妇400例;排除双胎妊娠及孕前糖尿病。根据孕前BMI分为两组,每组200例。BMI≥24kg/m~2为超重或肥胖组(A组),18kg/m~2≤BMI<24kg/m~2为体重正常组(B组)。分析两组孕妇妊娠至24周体重增加与GDM之间的关系。结果400例中,妊娠24周GDM 76例(19.0%),体重增加(9.5±1.8)kg;非GDM 324例,体重增加(5.6±1.3)kg;GDM孕妇体重增加明显(P<0.05)。A组GDM发病率高于B组(23.0%vs.15.0%)(P<0.05)。结论 PCOS患者孕前超重或肥胖促进GDM的发生,孕早中期体重增加过快是导致GDM更重要的原因。
Objective To investigate the relationship between weight gain and gestational diabetes mellitus (GDM) in pregnant women with polycystic ovary syndrome (PCOS) before 24 weeks gestation. Methods 400 cases of PCOS pregnant women scheduled for obstetrics and gynecology clinics in our hospital were selected. Exclusion of twin pregnancy and pre-pregnancy diabetes mellitus. According to pre-pregnancy BMI is divided into two groups of 200 cases each. BMI≥24kg / m ~ 2were overweight or obese (group A), 18kg / m ~ 2≤BMI <24kg / m ~ 2were normal weight group (group B). The relationship between weight gain and GDM between the two groups of pregnant women at 24 weeks of gestation was analyzed. Results Among the 400 cases, GDM was found in 76 pregnant women (19.0%) at 24 weeks gestation, and the weight gain was (9.5 ± 1.8) kg. There were 324 cases of non-GDM and 5.6 ± 1.3 kg body weight gain. The body weight of pregnant women with GDM increased significantly (P <0.05). The incidence of GDM in group A was higher than that in group B (23.0% vs.15.0%) (P <0.05). Conclusion PCOS patients overweight or obesity before pregnancy to promote the occurrence of GDM, early pregnancy and early weight gain too fast is leading to more important cause of GDM.