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目的:探究阿司匹林以及氯吡格雷在冠心病治疗中临床效果。方法:选取重庆市江津区第二人民医院在2013年2月至2016年2月收治的200例冠心病患者,随机分为观察组和对照组各100例。对照组患者采取阿司匹林治疗,观察组患者采取氯吡格雷治疗。观察两组患者血小板凝聚率情况、活化部分凝血酶时间、凝血酶原活动度、总有效率等指标,并将所得结果进行对比分析。结果:两组患者血小板凝聚率情况、活化部分凝血酶时间、凝血酶原活动度、总有效率方面比较,差异具有统计学意义(P<0.05)。结论:阿司匹林和氯匹格雷虽然在一定程度上都具有抗血小板凝聚效果,但后者更能提高疗效,而且治疗安全、不良反应率低。
Objective: To investigate the clinical effect of aspirin and clopidogrel in the treatment of coronary heart disease. Methods: A total of 200 patients with coronary heart disease admitted to the Second People ’s Hospital of Jiangjin District in Chongqing from February 2013 to February 2016 were randomly divided into observation group and control group with 100 cases each. Patients in the control group were treated with aspirin, and patients in the observation group were treated with clopidogrel. The platelet aggregation rate, activated partial thrombin time, prothrombin activity and total effective rate were observed in two groups of patients, and the results were compared. Results: The differences of platelet aggregation rate, activated partial thrombin time, prothrombin activity and total effective rate between the two groups were statistically significant (P <0.05). Conclusion: Aspirin and clopidogrel, although to a certain extent, have the effect of anti-platelet aggregation, but the latter can improve the curative effect, and the treatment is safe with a low rate of adverse reactions.