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目的探讨综合护理对丙泊酚复合瑞芬太尼全身麻醉(全麻)手术患者应激反应及认知功能的影响。方法 112例行全麻手术患者,随机分为对照组和研究组,各56例。两组患者均采用丙泊酚复合瑞芬太尼进行麻醉。对照组在围手术期进行常规护理,研究组在常规护理基础上实施综合护理。将两组护理效果进行对比。结果对照组术后过氧化脂质(LPO)水平明显高于研究组,差异有统计学意义(P<0.05)。对照组术前简易智力状态检查量表(MMSE)评分为(28.5±1.4)分,研究组为(28.4±1.5)分,两组术前MMSE评分对比差异无统计学意义(P>0.05)。术后1 d及3 d,对照组MMSE评分分别为(24.4±1.5)分和(26.4±1.3)分,低于研究组的(26.2±1.3)分和(27.6±1.1)分,差异有统计学意义(P<0.05)。结论在丙泊酚复合瑞芬太尼全麻手术患者围手术期实施综合护理可有效减轻患者应激反应,促进认知功能快速恢复。
Objective To investigate the effects of general nursing on stress response and cognitive function in patients undergoing propofol combined with remifentanil under general anesthesia (general anesthesia). Methods A total of 112 patients undergoing general anesthesia were randomly divided into control group and study group, with 56 cases in each group. Both groups were anesthetized with propofol and remifentanil. The control group underwent routine nursing during the perioperative period. The research group conducted comprehensive nursing care based on routine nursing. The two groups of nursing effects were compared. Results The level of LPO in the control group was significantly higher than that of the study group (P <0.05). The MMSE score was (28.5 ± 1.4) in the control group and (28.4 ± 1.5) in the study group. There was no significant difference in the preoperative MMSE scores between the two groups (P> 0.05). The scores of MMSE in the control group were (24.4 ± 1.5) and (26.4 ± 1.3) on the 1st and 3rd postoperative days respectively, which were lower than those of the study group (26.2 ± 1.3) and (27.6 ± 1.1) Significance (P <0.05). Conclusion The implementation of comprehensive nursing in patients undergoing propofol combined remifentanil anesthesia in perioperative period can effectively reduce the stress response and promote the rapid recovery of cognitive function.