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探讨多序列相关系数的全参数模型估计、二阶段估计和ａｄｈｏｃ估计方法，用ｍｏｎｔｅ－ｃａｒｌｏ方法模拟了其估计的真实性，并进一步讨论了多序列相关系数在生物医学领域应用的意义。
The full parameter model estimation, two-phase estimation and adhoc estimation methods of multiple sequence correlation coefficients are discussed. The monte-carlo method is used to simulate the estimation of the multiple parameter correlation coefficients. The significance of the application of multiple sequence correlation coefficients in the field of biomedicine is further discussed.