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目的利用神经血管线圈评价颈动脉粥样硬化出血斑块、纤维斑块及破损斑块的关系。资料与方法选择在我院诊断颈内动脉颅外段狭窄的患者52例,利用头颈部神经血管线圈,通过头颈部三维时间飞跃法(3DTOF)磁共振血管造影(MRA)及斑块部位双反转恢复(double inversion recovery,DIR)快速自旋回波(turbo spinecho,TSE)T1WI和T2WI判断颈内动脉颅外段狭窄部位及狭窄程度、粥样硬化斑块有无破损、斑块内出血及纤维成分,将斑块破损组和无破损组内的出血、纤维斑块数量分别行χ2检验,判断两组内的出血、纤维斑块数量差异有无统计学意义。结果 52例中,检测出颈动脉狭窄部位85处,出血斑块18处,纤维斑块54处,破损斑块26处,斑块破损组和无破损组内出血和纤维斑块数量差异均有统计学意义(P<0.05)。结论出血斑块伴发斑块破损概率大,纤维斑块伴发斑块破损概率小,DIR TSE序列可以判断出血斑块和纤维斑块,并有效预测斑块的破损。
Objective To evaluate the relationship between hemorrhage plaque, fibrous plaque and damaged plaque in carotid atherosclerosis by using neurovascular coils. Materials and Methods Fifty-two patients with extracranial stenosis of internal carotid artery diagnosed in our hospital were selected. Using the head-and-neck neurovascular coils, three-dimensional time-of-flight (3DTOF) magnetic resonance angiography (MRA) Dual inversion recovery (DIR) T1WI and T2WI were used to determine the location and extent of extracranial stenosis, the presence or absence of atherosclerotic plaque, the plaque hemorrhage and Fiber composition, the plaque damage group and non-damaged group of hemorrhage, the number of fibrous plaque were χ2 test to determine the two groups of bleeding, fibrous plaque number difference was statistically significant. Results Among the 52 cases, 85 sites of carotid stenosis, 18 hemorrhage plaques, 54 fibrous plaques and 26 damaged plaques were detected. There were statistically significant differences in the number of hemorrhage and fibrous plaque in plaque-damaged and non-damaged groups Significance (P <0.05). Conclusions The probability of lesion associated with plaque rupture is high, and the probability of plaque rupture associated with fiber plaque is small. DIR TSE sequence can identify hemorrhagic plaque and fibrous plaque, and predict the plaque damage effectively.