Modified Liangfu granule exhibits anti-cancer effects in gastric cancer by regulating apoptosis-rela

• 作 者: Ya Li Lingqun Zhu Fengqin Shi
• 机 构: DepartmentofOncologyandHematology,KeyLaboratoryofChineseInternalMedicineofEducationalMinistryandBeij
• 出 处: 中医科学杂志(英文)
• 发表日期: 2019年4期
• 关键词: Modified Liangfu granule Gastric cancer Caspase-3 E2F1 E2F3
• 基金项目: the National Natural Science Foundation of China(81573959),the Capital Health Research and Development of Special Fund(2016-1-4171).

Objective:To investigate the anti-cancer effects and mechanism of modified Liangfu granule(MLFG)in BGC-823 gastric cancer cells.Methods:The drug serum was extracted from abdominal aorta of Wistar rats treated by cyclophosphamide,dioscin,MLFG(high-,medium-