儿童特发性嗜酸粒细胞增多综合征1例

• 作 者: 李微娜 尤海龙 杨清然 刘野 张云峰 成焕吉
• 机 构: 吉林大学白求恩第一医院小儿呼吸一科,吉林大学白求恩第一医院病理科,
• 出 处: 中国实用儿科杂志
• 发表日期: 2012年03期
• 关键词: 嗜酸粒细胞增多 发性 临床综合征 受损者 器官 腹腔积液 伊马替尼 消化道内镜检查 骨髓象 消化道

特发性嗜酸粒细胞增多综合征(idiopathichypereosino-philicsyndrome,IHES)又称高嗜酸粒细胞综合征(idiopath-iceosinophilia),由Hardy和Anderson于1968年首先提出,是一种病因不明,以外周血嗜酸粒细胞增多、多脏器受累为特征的临床综合征,多发生于中年以上男性,预后较差,而儿童和青少年罕见。儿童IHES临床表现不典型,合并多器官受损者少见。现报告1例以消化道为首发症状并合并多器官受损的IHES患儿。

Idiopathic eosinophilic syndrome (idiopathic hyperoxicosyndrome, IHES), also known as hyperactive eosinophilic syndrome (idiopath-iceosinophilia), first proposed by Hardy and Anderson in 1968, is a cause of unknown, peripheral Blood eosinophilia, multiple organ involvement is characterized by clinical syndrome, mostly in men over the middle age, the prognosis is poor, while rare in children and adolescents. Clinical manifestations of children with atypical IHES, multiple organ damage combined rare. A report of 1 case of IHES with digestive tract as the first symptom and multiple organ damage was reported.