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Cajal间质细胞(ICC)是分布在消化道自主神经末梢和平滑肌之间的一类特殊细胞,是胃肠道慢波的起搏细胞,是胃肠运动的pacemaker,它推进电活动的传播以及介导神经信号传递,控制胃肠道自主神经运动功能近年来在人和动物膀胱中已证实存在ICC样细胞,其功能研究是最近研究的热点。ICC样细胞证实具有和胃肠ICC一样的耦联及神经调节功能的结构基础和功能特点,其是否具有起搏特性值得期待。
Cajal interstitial cells (ICC) is a special type of cells distributed between the digestive endothelium and smooth muscle. It is a pacemaker of the gastrointestinal tract and is pacemaker of gastrointestinal motility, which promotes the spread of electrical activity and In recent years, ICC-like cells have been identified in human and animal bladder, and their function is a hot topic in recent research. ICC-like cells demonstrate the structural basis and functional characteristics of the same ICC-like coupling and neuromodulation as gastrointestinal ICC-like cells, and its pacing properties are worth looking forward to.