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目的探讨维生素D在老年2型糖尿病患者中的作用。方法筛选没有接受胰岛素治疗以及服用过维生素D的老年2型糖尿病患者105例,其中维生素D缺乏的患者84例为研究组,给予每周一次维生素D3,至少服用8周;维生素D水平正常的21例为对照组;分析相关数据。结果 80.00%的老年2型糖尿病患者存在维生素D缺乏现象,患者BMI、FPG明显高于对照组(P<0.05)。研究组平均接受治疗84.13 d后,所有患者的血清25(OH)D水平均高于20ng/m L;与治疗前对比,FBG和QUICKI差异有统计学意义(P<0.01);但是在减少Hb A1c,FIN以及HOMA-B方面,差异并没有统计学意义(P>0.05)。结论老年2型糖尿病患者更容易出现维生素D缺乏现象,对于老年2型糖尿病患者补充维生素D能够降低患者空腹血糖。
Objective To investigate the role of vitamin D in elderly type 2 diabetic patients. Methods A total of 105 elderly patients with type 2 diabetes who did not receive insulin and vitamin D were enrolled. Among them, 84 patients with vitamin D deficiency were treated with vitamin D3 once a week for at least 8 weeks; 21 with normal vitamin D levels Cases for the control group; analysis of relevant data. Results 80.00% of elderly patients with type 2 diabetes had vitamin D deficiency. The BMI and FPG of patients were significantly higher than those of the control group (P <0.05). The average serum 25 (OH) D level of all the patients in the study group was higher than 20ng / m L after 84.13 days of treatment. The difference of FBG and QUICKI between the two groups was statistically significant (P <0.01) A1c, FIN and HOMA-B, the difference was not statistically significant (P> 0.05). Conclusions Vitamin D deficiency is more likely to occur in elderly type 2 diabetic patients and vitamin D supplementation in elderly type 2 diabetic patients can reduce fasting blood glucose.