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目的:讨论妊娠期糖尿病(GDM)患者糖化血红蛋白(HbA1C)和超敏C反应蛋白(hs-CRP)联合检测的临床意义。方法:收治GDM孕产妇130例,选择同期无其他合并症的健康孕妇130例作为对照组。对各组研究对象空腹血清中的超敏C反应蛋白和糖化血红蛋白的含量进行测定,并对各数据进行统计分析。结果:GDM组的HbA1C及hs-CRP水平均显著高于对照组,两组比较差异有统计学意义(P<0.01)。GDM组在妊娠期高血压疾病、羊水过多明显高于对照组,比较差异均有统计学意义(P<0.05)。结论:联合检测HbA1C及hs-CRP水平有利于GDM的早期诊断,为评价患者病情、预后及指导治疗等提供了重要的参考价值。
Objective: To discuss the clinical significance of combined detection of HbA1C and hs-CRP in patients with gestational diabetes mellitus (GDM). Methods: One hundred and thirty cases of pregnant women with GDM were treated, and 130 healthy pregnant women without other complications were selected as the control group. The contents of Hs-CRP and HbA1c in fasting serum of each group were determined, and the data were statistically analyzed. Results: The levels of HbA1C and hs-CRP in GDM group were significantly higher than those in control group. There was significant difference between the two groups (P <0.01). GDM group in hypertensive disorder of pregnancy, polyhydramnios was significantly higher than the control group, the difference was statistically significant (P <0.05). Conclusion: The combined detection of HbA1C and hs-CRP levels is helpful for the early diagnosis of GDM and provides an important reference value for evaluating the patient’s condition, prognosis and guiding treatment.